HT + GLP-1 = The ultimate midlife stack?

Timeline of a trend my Spidey Sense finds concerning

Photo by Raghavendra V. Konkathi on Unsplash

The first video I saw was posted on May 14 on Instagram. Leanne Duncan, a hormone and fat loss coach with 67.5K Instagram follower, who runs a “peptide/hormone program”, posts a Reel with her equally gorgeous partner.

They walk toward the camera, hand-in-hand, smiling as if they both have a secret. The words on the screen read: “At 55, we didn’t need a couples retreat. We needed microdosing, GLP-1 peptides, NAD and muscle.”

They kiss. He cups her behind. She leaps onto him, wrapping her legs around his waist. She gets down. They hug. They kiss again.

The caption reads like an infomercial:

“Let me be real with you. I already knew what to do. I’ve been in shape. I know hormones. I’m an integrative practitioner. This is literally what I do. But menopause doesn’t care how much you know. I was doing everything ‘right’ and still felt off. Tired. Puffy. Not myself. And honestly, that disconnection showed up in our marriage, too.

Then I started microdosing GLP-1 peptides. That was the shift.”

(Btw: Her hubby also “felt off,” and the microdosing worked for him too. Now their marriage is apparently even more swell.)

She goes on to talk about weight, inflammation, insulin sensitivity and then, boom: “…and finally letting my hormone therapy work the way it was supposed to”.

My Spidey senses were already tingling, but here is where the needle scratched off the record for me. Um, pardon? Your hormone therapy needs something else (other than lifestyle changes) to “work the way it was supposed to”?

Dr Mary Claire Haver joins in

Then on May 29, Dr. Mary Claire Haver sent out a Substack titled: “What I Got Wrong About Menopause and Metabolism, and What I Recommend Now: GLP-1s and Hormone Therapy—A New Era in Menopause Metabolic Care.”

But first, a little context on the whole GLP-1 thing: